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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

但是在对遗骸进行分析后,研究人员发现这些坟墓被重复利用了多次。有些坟墓中包括有10多个的死者,多次的重复埋葬有待于进一步的研究,研究人员写到。
['medl]

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: “人情味”营销模式走红家具行业
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

n. 谷物,小麦,玉米
在新的领导层刚刚接手之际,中国的政治体制会继续将注意力放在保持稳定上,但经济弹性的降低,可能挫败北京方面在这方面的意图。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 天津将建至雄安新区城际铁路
Open Access Perspective

Soft matter science and the COVID-19 pandemic

如果你觉得现在的杜兰特骨瘦如柴,那你得瞧瞧他在蒙特罗斯基督教会学校时的瘦弱身板。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 仿古砖+现代风“砖”攻80后90后
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

As a national exam with more than 1 million test takers every year, the National Postgraduates Entrance Examination is very important for students' academic life, and cheating incidents have been exposed from time to time.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Izabella Kaminska
俄罗斯为世界上第十大经济体,除了天然气(碳氢化合物),经济贡献甚微。腐败和寻租行为使经济蒙受巨大损失。它依然沿用着苏联时代的基础设施,并且满足国民教育、医疗需求的能力正急速下滑。
Life's ups and downs
6.摄影记者

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

stress
Detroit Three: The other two Michigan-based manufacturers still face bumps. General Motors copes with continued fallout from its ignition switch recall while Ford fights through the most aggressive launch period in the company’s history.
Singer Susan Boyle came undone -- literally, when her trousers popped open at a soccer match as she waved a Celtic fan above her head in Scotland. The "Britain
每个伟大的侦探都需要专属于自己的经典故事。对于福尔摩斯而言,这个故事是《巴斯克维尔的猎犬》。对于阿加莎?克里斯蒂笔下龟毛的比利时侦探赫克尔?波洛而言,这个故事是《东方快车谋杀案》——故事讲述了一个嗜血的恶棍在驶向巴尔干半岛的列车上杀死了一个有钱的商人。真相果真是如此吗?西德尼?吕美特曾在1974年将该故事拍成了一部备受喜爱的电影,强大的演员阵容包括肖恩?康纳利、英格丽?褒曼和阿尔伯特?芬尼(饰演侦探波洛)。如今肯尼思?布拉纳自己戴上了侦探波洛的大胡子,披挂上阵,同时又担当幕后导演。这部新版电影的演员有约翰尼?德普、黛西?雷德利、米歇尔?菲佛、佩内洛佩?克鲁斯和朱迪?丹奇。这个故事还能挖掘出什么新内容呢?也许会有。不过,即使没有,阿婆的粉丝也肯定会去看。这部电影将于11月3日在英国上映,11月10日在美国、中国和土耳其上映,11月30日在中国香港和新加坡上映。(资料来源:二十世纪福克斯电影公司)

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

People who are skeptical about this argument just need look at smartphones and personal computers, which have served as the technological driving force of the past century.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 建立房产市场调控长效机制
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

最畅销车型

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 稳投资 有储备有信心
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

对“最后的共同祖先”的认识发生了改观
As a result, 39 percent of the post-90s generation tries to avoid the negative effects of mobile phone use through measures like turning off app notifications, intentionally limiting the frequency of social media interactions and staying away from social media entirely in certain situations.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Her real-life sister Lexie often accompanies her dressed as Elsa's sister Princess Anna from the movie, and her best friend steps in when Lexie isn't available.
The pickup in consumption in turn will entice businesses to hire and invest more to keep up with rising sales. The result: The U.S. is likely to grow more than 3% for the first time since 2005.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

['k?pirait]
保安负责监管烘焙坊一次能容纳多少蛋糕狂热者。当然,木兰烘焙坊并没有因为人多而怨气冲冲。烘焙坊把电视剧纪念品展览于多家分店的墙上,并引以为豪。现在,木兰烘焙坊以香蕉布丁而闻名,但他们的最初成功应该归功于凯莉·布拉德肖以及红天鹅绒纸杯蛋糕。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

issue
Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.
单词immunity 联想记忆:
尽管人工智能取得了突破,阿里巴巴集团董事局主席马云却认为,人类不需要惧怕机器。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 朝阳政务服务中心延时两小时
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Canadian schools continue to lose ground. Only three remain in the ranking compared with five last year and all fall about six places. Among these, Rotman School of Management at the University of Toronto is the highest ranked at 65, while Smith School of Business at Queen’s University is bottom of the table in 100th place.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

周边环境:斯托宁顿位于康涅狄格州东南部的小纳拉甘西特湾(Little Narragansett Bay),从哈特福特(Hartford)和罗德岛的普罗维登斯(Providence, R.I.)开车约1小时可达,从纽约市开车约3小时。这里曾是一个具有悠久历史的繁忙港口,至今仍然保留着一支商业捕鱼船队,有几个分布着殖民式和联邦式建筑的历史区,以及一个繁荣的航海社区。在该镇的一端有个小型的公共海滩,而在另一端罗德岛的沃奇·希尔(Watch Hill)则有个大得多的海滩,开车大约20分钟可到。这栋希腊复兴式房屋带有此类建筑必不可少的爱奥尼亚柱和山形墙上的扇骨半圆窗,房屋就坐落在市镇中心。
飓风厄玛

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Sixty-one percent of Chinese college students who graduated in 2014 are satisfied with their current jobs, a survey has revealed.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The three-day China Development Forum 2016 kicked off in Beijing.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

She was also recognised for being the youngest recipient of the Ripple of Hope Award from the Robert F. Kennedy Center for her charity work.
3. Kraft. Brand love: -10% / Rank: 11
Or, this year, to be women with a story to tell about abuse, sexual or otherwise — a couple of whom shared #MeToo moments in our pages. Carlotta Gall told the story of Henda Ayari, a French citizen of North African heritage and anti-Salafist activist who accused a prominent Oxford professor of raping her.
2.German: 22.2 percent increase

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

X-Men: Apocalypse is said to hit theatres on May 27, 2016.
"If it (transforming the economic development mode) only results in empty talk instead of being implemented, then economic development cannot be promoted in a sound and rapid way, and may even not be sustained." LI YIZHONG, member of the CPPCC National Committee and former minister of industry and information technology
I mean, is it worth to be a No. 8 seed with Serge Ibaka and Jeff Green leading the way? Maybe it is. This all just seems awfully backwards.
和过去几年相比,2013年信心受到动摇的时候少了,但市场依然很容易受到影响。OppenheimerFunds的首席经济学家韦布曼(Jerry Webman)表示,虽然2013年的信心要强于以往,但全球各地也不都是这样。
Domestically, an increasingly active middle class is generating pressure for more accountable governance. Mounting inequalities have nurtured a sense of injustice; 200m migrant workers remain second-class citizens and corruption is worsening. Tackling these problems is urgent, but China's economic successes have fostered an unwarranted self-confidence. Instead, motivated by the Arab spring, the system has moved aggressively to contain any social discontent that might spark more politically sensitive movements.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 乡村民宿:共享经济新体验
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Do you feel any of your worksare underrated or wished was a little bit more popular?
Here's how the pay of prime ministers and presidents of the world's biggest economies stacks up, according to official data and converted into US dollars at market rates.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

James Bond Themes 6. "A View to a Kill" by Duran Duran

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 中美光伏贸易战加大行业风险
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

而分子马达将会为医药和能源领域带来巨大的潜力。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

安妮-西尔万沙萨尼(Anne-Sylvaine Chassany)
5. Women keep rising.
What Mr Ravenscroft liked about it when he was choosing his graduate career path was that it of-fered the best of two worlds. He would be fast-tracked into the classroom, earning a salary, being mentored by an executive from the private sector and making contacts with business; in return, he would commit to teaching for two years and complete a teacher training qualification.
时间:2011-11-04 编辑:Lily

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Two-thirds of this year’s deals are trading above their issue price. On average, 2017’s class of US IPOs have risen in value by about double the S&P 500, at 20 per cent, according to Renaissance Capital, which runs IPO-focused exchange traded funds.
克普克认为,这些情况或将发生变化,而它们的意义被低估了。
Truck wars: Awards aside, Ford’s aluminum pickup is hard to build and slow to sell, leaving an opening for Ram’s fast-rising 1500 while Nissan tries to forget the failure of its first full-size truck when it launches the second-generation Titan with the biggest of big rig styling. The industry’s biggest secret is revealed by veteran executive John Krafcik in Automotive News: In the
Remedy: When we make a major decision such as accepting (or turning down) a job offer, we tend to exercise confirmation bias. If we think we made a good choice, we prioritize information that supports this view and if we fear we’ve made a mistake, we zero in on intel or impressions that reinforce this gut feeling. If you habitually doubt your competence when it comes to making career decisions, the issue is less about the subjective quality of your past choices and more about building confidence in your ability to guide your career in a satisfying direction and exert some degree of control over the outcomes of your choices. Addressing this could involve recalling the circumstances under which you made a particular choice and the priorities you held at the time and noting how they differ from the circumstances and priorities under which you’re evaluating those decisions. It could also involve working with a career coach to identify patterns in your decision-making and to help you bolster areas in which you’d like to increase your confidence – risk taking or negotiation, for example.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

安娜的工资也就是巴西的最低月薪,仅330美元。因此门票对普通老百姓来说实在过于昂贵。
Local-level work experience will advantageous for applicants, with personnel with more than two years of experience at this level given some advantage.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 全国房贷利率连续18个月上涨
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Managers are able to reward their subordinates in unique, personalized ways thanks to the budget they receive from corporate. Two examples of past bonuses: free trail rides at an equestrian stadium and a barbeque with lassoing and horseshow throwing lessons.
Emily Ratajkowski managed to steal the show, opting for a seriously saucy twist on the classic ballgown. Opting for a semi-sheer lacey black number, the We Are Your Friends actress ensured her world-famous figure was on display.
Apple Inc., Alphabet Inc.'s Google, and Coca-Cola Co. topped the list of the world's 100 most valuable brands in 2016, while technology and automotive brands dominated the overall rankings, according to a new report from brand consultancy Interbrand.
而在进口一侧,不论以人民币还是美元计,情况都愈发糟糕。
但是美国加州公务员退休基金(Calpers)的高级投资组合经理兼全球治理主管安妮?辛普森(Anne Simpson)却相信,库克的道德立场不仅仅是种姿态。她说:“他对作秀技巧的漠视自有其魅力。蒂姆?库克将苹果这种优雅和卓越的理念应用到这些新的领域。”加州公务员退休基金是苹果的重要股东。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 吸音涂料的施工及注意事项
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Best Companies rank: 1
The former Miss World Priyanka Chopra stands 9th on the world's most beautiful women of 2015 list. She is an Indian film actress and singer. She is one of Bollywood's highest-paid actresses and one of the most popular and high-profile celebrities in India. She has received numerous accolades, including a National Film Award for Best Actress and Filmfare Awards in four categories.
The top 10 Weibo celebrities now have a combined 40 million followers. One of the most famous online figures, Papi Jiang, already signed a contract for video ads worth a staggering $3.4 million.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 资本退潮 长租公寓重新洗牌
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The Republican candidate appeared unsure at times and occasionally stumbled over his lines as if struggling to remember his briefing notes. He began sweating as Obama, aggressive from the start, got the better of him during exchanges on Iran, Iraq and Russia as well as on US military spending.
位于第三位的是收入5.95千万的Fleetwood Mac,尽管这支乐队有三位男士,它也以拥有两位备受瞩目的女星为荣,她们是史蒂薇.妮克丝和最近回归的克莉丝汀麦克,是她们造就了本次上榜。乐队的巡回演唱会On With The Show在打分期间共有86场演唱会,在每个城市平均挣得超过1百万。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

“只要总体市场仍然相对积极,只要交易继续执行良好,我们继续预期今年余下时间会保持健康的交易量,”高盛(Goldman Sachs)美洲股票资本市场主管戴维?路德维格(David Ludwig)表示。
中国领导人会刺激国有经济。资助更多的扩张性增长项目,比如用以支持城镇化发展的基础建设的投资,包括大量的房屋、学校、公路等方面的建设。
While oil prices may rebound in 2015, they almost certainly won't return to $100 a barrel any time soon, barring a geopolitical crisis in a major petroleum-producing region. So the gift will keep giving this year and further feed an accelerating U.S. recovery.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

持续推进大众创业、万众创新。
Ann Hand
美国电话电报公司

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 地板行业如何不再“谈醛色变”
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 品质成LED产品出口新绿卡
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

本文列举了16种我本人几乎每天都会使用的应用软件,我还将在本文中讨论为什么你也应该使用它们。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

JM家庭企业公司:忠实员工奖励度假

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

与此同时,国内互联网用户已经养成了手机支付的习惯,去年用手机支付的用户数量飙升到了4.69亿,同比前一年增长了31.2%。
grant

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

(美联社)波多黎各,圣胡安市 - 波多黎各新总督周一宣誓就职,作为美国领土许多人认为要为新的紧缩措施做准备,并为该岛摆脱严重的经济危机重新推动建州或独立。
6、A股保卫战
用这个背带背孩子更加方便舒适。
添加方式2.搜索微信号ikekenet添加即可。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Homing in on a brand that excels at making the kind of vehicle you’re looking for is an efficient way to focus your shopping and find the best car for you. The 2016 U.S. News Best Vehicle Brand awards recognize the best brands in four categories: Cars, SUVs, Trucks and Luxury.
Edgar Wright’s Baby Driver is one of the most entertaining thrill rides of this year, this decade. This century.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 卫浴电商模式助力行业变革
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

People who are skeptical about this argument just need look at smartphones and personal computers, which have served as the technological driving force of the past century.
How do you feel about workingwith Ei Aoki again in Aldnoah?

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

据第三方市场情报公司IDC日前公布的数据显示,去年中国智能手机制造商华为、OPPO以及vivo的年出货量大增,使得三家企业都成为了世界前5大智能手机制造商。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

价值增长最快的品牌
adj. 代理的,副的
8. How to dip dye hair
Apple Inc. CEO Steve Jobs introduces the iPad 2 on stage during an Apple event in San Francisco, California in this March 2, 2011,

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Six regions recorded GDP growth less than 7 percent, with China's north-eastern rust belt Liaoning province at the bottom with negative growth.
彭博(Bloomberg)的调查分析此前预计1月份中国CPI应上升1.9%。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

6. You don’t just pass in front of the TV if i’m watching football, you better crawl on the floor.
"We'll start with a broad list and then begin to narrow it," Podesta told the Boston Globe. "But there is no question that there will be women on that list."
2015年3月,前任首相卡梅伦在CNNMoney的收入排行中以14万2500英镑(在当时约合21.48万美元)的年收入位列第五,而梅今年只排到第七。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

CareerCast.com, a career website owned by Adicio Inc., ranked 200 jobs from best to worst based on five criteria: physical demands, work environment, income, stress, and hiring outlook. The firm used data from the Bureau of Labor Statistics and other government agencies to determine the rankings. As in prior years, the 200 jobs were selected for their relevance in the current labor market as well as the availability of reliable data.
n. 紧张,拉紧,血统
The Cnzz.com report also discusses the problem of the 'free-to-play' business model that's prevalent in China's online game sector. While many games companies in the U.S., for example, charge subscription fees, most Chinese games utilize the free-to-play model, which allows players to try out a game without paying. The longer players stay in the game, the more likely they will be to pay for in-game items to move up into higher levels of play. But that also means that people who spend the most money are the best performers.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 驳家装O2O与互联网装修的十大谬论
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

As for the fortunes of the gig economy, the UK will be a key country to watch. The government is due to respond to an independent review into whether British law is keeping up with this new trend. Bold policy action — either in favour or against online labour platforms — now seems less likely given the fragility of the government and the time-consuming nature of Brexit.
坚决打好蓝天保卫战。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

vi. 领先
国家已出台多项措施来推动新能源汽车,包括免税、发放购车补贴,以及要求政府部门购买更多的新能源汽车。
The invulnerable singer broadened into a wider emotional palette – musical too, with guitars and brass lacing through synthetic beats and dub effects. It could recall art-rock godmother Kate Bush (see the single "Green Light").

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

《请以你的名字呼唤我》
The best bosses understand the art of delegation. My commenter said something along the lines of, “They’ve fired themselves from their previous job,” meaning that they don’t interfere in the day-to-day and minute-to-minute workflow or processes. In essence, learning to delegate instead of micromanage is about trust。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

A string of other Victoria's Secret models have also been banned from the country including Julia Belyakova, Kate Grigorieva and Irina Sharipova - all from Russia - and Ukraine's Dasha Khylstun.
"People should just never walk away and leave their animals," Ms Lewis said. "Everyone has a legal obligation to look after animals in their care."
单词securities 联想记忆:

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

苹果公司和中国移动之间的协议尘埃落定之后,有关苹果下一款重大产品发布的供应链传言又开始浮现。Digitimes报道称,据“上游供应链的消息”,苹果公司正酝酿在明年5月发布一款5英寸屏幕的iPhone 6“平板手机”,在明年10月发布一款大尺寸平板电脑。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

失业率的大幅下降的实际效果将会有所体现
On our increasingly human-dominated planet we can still learn much from the lives of other species. The discovery this year that the Greenland shark lives for 400 years, making it the longest-living vertebrate, puts our hectic lives into perspective.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

国家新闻出版广电总局官员表示,中国电影业在2016年经济发展“新常态”下保持了稳定的发展势头。
The Cems masters in management, the international programme provided through a network of 30 business schools, is ninth, down five places from 2015, when it was last ranked.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

都不是。1772年,一场空前的危机击中了阿姆斯特丹:一家受人尊敬的荷兰投资银团对不列颠东印度公司(British East India Company)股票的投资变成了一场灾难。
Against: Opening so early in the year outside of awards season could hinder its chances.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

优秀老板看起来都会拥有的一个关键是:他们都是解决问题的高手。他们不仅能够发现问题,并能头脑风暴出成功创新的方法来解决问题。
国内生产总值达到74.4万亿元,增长6.7%;

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

jar

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

response
Sliced into eight pieces, the pizza works out to $250 per slice, meaning it costs roughly $50 per bite.
史蒂夫?乔布斯(Steve Jobs)去世后的三年中,维权投资者对苹果发起了攻击,一些人对没有乔布斯的苹果是否还能成功也失去了信心,但现年54岁的库克一直沉着应对。今年,他走出了前任的影子,以自己的一套价值观和议程给苹果公司打上了印记:他引进了新鲜人才,改变了苹果管理巨额现金的方式,扩大了苹果与外部的合作,更加关注社会问题。
我们准备今年在香港和内地试行“债券通”,也就是说允许境外资金在境外购买内地的债券,这是第一次。香港是近水楼台先得月。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Stand: Facebook CEO Mark Zuckerberg took a stand for immigration reform

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

For those outside the scientific community, the response to the retraction has been mixed.
“这可能影响他们一生。”
8.Suicide Squad

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

单词posture 联想记忆:
It's important to remember that even when the overall number of jobs goes down, some companies are still adding workers -- it's just that others are cutting even more.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

纳粹势力席卷西欧,一场入侵迫在眉睫,然而一方面民众毫无准备,一方面国王还心存怀疑,认为王位陷入了自己党派设下的阴谋之中。丘吉尔必须承受至暗时刻,团结全国,改写世界的历史进程。
One such development is 60 Water Street in Dumbo, a 290-unit rental with a 24-hour concierge and a roof deck offering Manhattan views. Leasing begins next month, with rent for a two-bedroom starting at a jaw-dropping $6,018 a month. “People want that condo-like living, even though they’re renting and not owning,” said Jodi Ann Stasse, the managing director of new developments for Citi Habitats.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

经济运行缓中趋稳、稳中向好;

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Everyone on Wall Street, Main Street and Washington keeps forgetting the fundamentals of market cycles. Please remember: Investors Business Daily's Bill O'Neill, author of 'How to Make Money in Stocks, ' says market cycles average 3.75 years up, nine months down.
Guangdong has cemented its position as the country's largest provincial economy for the 28th consecutive year, with its gross domestic product (GDP) exceeding 7.9 trillion yuan in 2016.
位于华盛顿特区的乔治敦大学(Georgetown University)麦克多诺商学院(McDonough business school)重新回到了定制课程排行榜的第15位,去年,该校因客户调查反馈率低而未上榜。只有3所学校是首次登上定制课程排行榜,包括排名第60位的伦敦卡斯商学院(Cass Business School)。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

3 . 《歌剧魅影》( T h e Phantom of the Opera )是 由安德鲁·韦伯(Andrew Webber)作曲的著名音乐剧,剧中的男主人公“魅影”(Phantom)的右脸上戴着一副面具。
14. 《与外婆同行》(Grandma),导演:保罗·韦兹(Paul Weitz)。
China's box office sales have increased from 1 billion yuan to 40 billion yuan in the past decade as the industry has adopted more market-oriented reform measures.
1997:H5N1传染人类1997: H5N1 Infects Humans

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

The report found that students majoring in art, agriculture and engineering were more willing to start businesses, while those majoring in history and science showed relatively low interest.
到了20世纪下半叶,随着歧视逐渐减少(比如在大学入学方面),白人的正式特权地位也在渐渐丧失。但是工资的增长、社会安全网的扩大以及新的受教育机会有助于弥补他们的损失。大多数成年白人都比父母更富裕、更成功,他们相信子女们会过得更好。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

v. 加强,变坚固
Beauty and Evolution
单词population 联想记忆:

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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The film critics of The New York Times — Manohla Dargis and A. O. Scott — share their picks for the best movies of the year.

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